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SAXENDA

Saxenda is a medication approved for weight management as an adjunct to diet and exercise.

It belongs to a group of medications known as glucagon, saxenda is very similar to a GLP-1, a hormone that occurs naturally in the body which is released in response to food intake and acts as a physiological regulator of appetite and digestion.

GLP-1 that is produced by our body is rapidly broken down, resulting in a short half life of less than 2 minutes.

Saxenda mimics GLP-1, but is much longer lasting, with a half life of about 13 hours when injected. Because of its long half life, it can act on the GLP-1 receptor for longer, exerting its physiological effects.

GLP-1 receptors can be found in several organs, including the brain, pancreas, gastrointestinal tract, heart, vasculature and kidneys.

Saxenda works by binding to the receptors in the arcuate nucleus of the hypothalamus in the brain, where it stimulates satiety and inhibits hunger neurons.

Because of this, you eat less, leading to weight loss

What is the use of Saxenda?

If you are obese, or overweight with weight-related medical problems (such as high blood pressure, high cholesterol, or type 2 diabetes), this medication can help with weight loss, and keeping the weight off.

Saxenda is meant to be used alongside diet control and exercise.

How to use Saxenda?

Saxenda is an injectable medicine usually given once per day. It is injected under the skin at any time of the day (usually in the morning), with or without a meal.

There are a variety of places you can inject, but most commonly, it is injected into the skin around the abdomen.

It comes in a prefilled injection pen with disposable needles. The doctor will teach you exactly how to inject this medication, and to use a different spot to inject each time.

How much does Saxenda Cost?
$90.00 per pen.
Who is suitable for use of Saxenda?
You are suitable if you are
• overweight persons with weight-related medical problems (e.g. high blood pressure, high cholesterol, or type 2 diabetes)
• obese persons with or without weight-related medical problems

Who should not use Saxenda?

If you are currently on insulin for treatment of Diabetes, Saxenda may not be suitable for you.

The safety of Saxenda has not been studied when taken with other prescription, over-the-counter, or herbal weight-loss product.

It is not known if Saxenda can be used safely in people who have had pancreatitis.

Saxenda is not recommended for use in children.

Are there any side effects when using Saxenda?

The most common side effect of Saxenda are gastrointestinal and can include nausea, diarrhoea, constipation, vomiting, abdominal pain and flatulence.

Some patients may get headaches, low blood sugar, dizziness, fatigue or changes in taste as well.